Opioid Drug Safety Research

Opioids are a group of prescription drugs used to treat pain conditions; however the efficacy and safety of their use in treating chronic non-cancer pain has been widely questioned due to a lack of long-term studies, the availability of various opioid types and potencies on the market, and uncertainty on appropriate dosing. Given that Canada and the United States have the highest per capita consumption of opioids worldwide, this area required further evidence.

The ODPRN has conducted several population-based studies on the safe and appropriate use of opioids in Ontario by investigating the overall trends and geographic variation in opioid prescribing and related deaths, and the impact of policy and education interventions on important patient outcomes.

New Research

Impact of timing of methadone initiation on perinatal outcomes following delivery among pregnant women on methadone maintenance therapy in Ontario

Methadone maintenance therapy (MMT) is used to treat opioid use disorder. In Ontario, MMT is a recommended treatment for pregnant women with opioid use disorder, yet little is known about the women who use this therapy throughout pregnancy and their outcomes.

This study examined whether timing of methadone initiation for pregnant women impacted outcomes for the mother and baby shortly after delivery.


Journal Article Research Minute In The News



All Research on Safety and Use of Opioids

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