Recent Research from the ODPRN

Journal Articles

Trends in varying modes of drug use in opioid toxicity deaths in Ontario from 2017 to 2021

This study assessed patterns of mode of drug use over time among people who died of opioid toxicity in Ontario and characterized demographic and clinical characteristics of decedents, and the circumstances surrounding their deaths.

September 22, 2023

Impact of national recommendations for routine pertussis vaccination during pregnancy on infant pertussis in Ontario, Canada: a population-based time-series study

In February 2018, Canada’s National Advisory Committee on Immunization (NACI) recommended antenatal tetanus–diphtheria–acellular pertussis (Tdap) immunization in every pregnancy regardless of previous Tdap immunization history. This study examined the impact of the NACI recommendation on rates of infant pertussis in Ontario.

August 31, 2023

Assessing the impact of the slow-release oral morphine drug shortages in Ontario, Canada: A population-based time series analysis

Slow-release oral morphine (SROM) is used to manage pain, and as opioid agonist treatment (OAT). This study evaluates the impact of several drug shortages that occurred for Kadian© (SROM-24) on people’s ability to remain on this medication.

July 8, 2023

Trends in opioid toxicity–related deaths in the US before and after the start of the COVID-19 pandemic, 2011-2021

This study characterizes the growing societal burden of unintentional opioid-related deaths in the US and examine patterns during the COVID-19 pandemic and across demographic subgroups of the population.

July 7, 2023

Public Reports and Tools

Characteristics of substance-related toxicity deaths in Ontario: Stimulant, opioid, benzodiazepine, and alcohol-related deaths

This report describes trends and circumstances surrounding fatal substance-related toxicities broadly in Ontario, combining data on deaths due to alcohol, stimulants, benzodiazepines, and opioids. 

September 14, 2023

Ontario Opioid Indicator Tool Update

This interactive online tool provides public access to indicators of opioid use, opioid-related harms, access to treatment and harm reduction in the province and has been updated with annual 2022 data and monthly data up to June 2023.

August 31, 2023

Safer Opioid Supply: A rapid review of the evidence

This rapid review of qualitative and quantitative peer-reviewed and grey literature publications describes the clinical outcomes of SOS programs, as well as the perceptions of clients and providers involved in the provision of these programs.

July 13, 2023

Opioid toxicity and access to treatment among adolescents and young adults in Ontario

This report examines (i) trends in opioid toxicity and treatment for opioid use disorder; (ii) demographic characteristics and circumstances surrounding opioid toxicity deaths; and (iii) interactions with the healthcare system prior to opioid toxicity death among adolescents and young adults aged 15 to 24 compared to individuals aged 25 to 44 years old.

June 27, 2023

Additional Resources

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