Publications & Reports

The ODPRN has been publishing peer-reviewed journal articles and preparing public reports since 2008. The ODPRN also completed a total of 12 drug class reviews.

  • Journal articles span multiple topics, and are typically freely accessible (i.e. open-access)
  • Research reports are prepared in response to research requests from the Ontario Public Drug Programs (OPDP) or are based on findings from ODPRN research. Although most reports remain confidential until the findings are prepared for peer-reviewed publication, some studies conducted by the ODPRN touch on current issues that require the rapid release of research information. These reports on high impact issues are released publicly to facilitate wider access to study findings.
  • Drug class reviews were based on an innovative framework that resulted in research findings synthesized to make recommendations to the OPDP regarding public drug reimbursement policies.

Publications and reports are listed below in chronological order.
You can also sort publications by type, clinical topic and research topic using the filter button next to the column header.

wdt_ID Title Publication Type Date Released Clinical Topic Research Topic Additional Resources
wdt_ID Title Publication Type Date Released Clinical Topic Research Topic Additional Resources
1 The characteristics of treated pulmonary arterial hypertension patients in Ontario Journal Article 01 Jan 2016 Cardiovascular Health Descriptive and Utilization Trends
2 Persistence with therapy among patients treated with warfarin for atrial fibrillation Journal Article 26 Nov 2012 Cardiovascular Health Drug Adherence
3 Low molecular weight heparin Drug Class Review 01 May 2016 Cardiovascular Health Policy analysis Research Summary
4 The influence of socioeconomic status on selection of anticoagulation for atrial fibrillation Journal Article 25 Feb 2016 Cardiovascular Health descriptive and utilization trends
5 Impact of the JUPITER trial on statin prescribing for primary prevention Journal Article 12 Aug 2013 Cardiovascular Health Policy analysis
6 Trends in the coprescription of proton pump inhibitors with clopidogrel: An ecological analysis Journal Article 26 Nov 2015 Cardiovascular Health Drug-Drug Interactions
7 Selective serotonin reuptake inhibitors and pulmonary arterial hypertension: A case-control study Journal Article 01 Feb 2012 Cardiovascular Health Real-world Safety and Effectiveness
8 Rates of hemorrhage during warfarin therapy for atrial fibrillation Journal Article 26 Nov 2012 Cardiovascular Health Real-world Safety and Effectiveness
9 Risk of incident diabetes among patients treated with statins: Population-based study Journal Article 23 May 2013 Cardiovascular Health Real-world Safety and Effectiveness Research Minute
10 Statins and the risk of herpes zoster: A population-based cohort study Journal Article 13 Nov 2013 Cardiovascular Health Real-world Safety and Effectiveness
11 Rates of ischemic stroke during warfarin treatment for atrial fibrillation Journal Article 19 Feb 2015 Cardiovascular Health Real-world Safety and Effectiveness
12 Chlorthalidone versus hydrochlorothiazide for the treatment of hypertension in older adults: A population-based cohort study Journal Article 19 Mar 2013 Cardiovascular Health Real-world Safety and Effectiveness
13 Ticagrelor and bradycardia: A nested case–control study Journal Article 07 Oct 2015 Cardiovascular Health Real-world Safety and Effectiveness
14 Comparative effectiveness of angiotensin-receptor blockers for preventing macrovascular disease in patients with diabetes: A population-based cohort study Journal Article 08 Jul 2013 Cardiovascular Health Real-world Safety and Effectiveness Research Minute
15 Macrolide-induced digoxin toxicity: A population-based study Journal Article 15 Jul 2009 Cardiovascular Health Drug-Drug Interactions
16 Beta-blockers trimethoprim-sulfamethoxazole and the risk of hyperkalemia requiring hospitalization in the elderly: A nested case-control study Journal Article 01 Sep 2010 Cardiovascular Health Drug-Drug Interactions
17 Trimethoprim-sulfamethoxazole–induced hyperkalemia in patients receiving inhibitors of the renin-angiotensin system Journal Article 28 Jun 2010 Cardiovascular Health Drug-Drug Interactions
18 The safety of proton pump inhibitors and clopidogrel in patients after stroke Journal Article 27 Dec 2010 Cardiovascular Health Drug-Drug Interactions Research Minute
19 Antidepressant use, serotonin transporter affinity, and reinfarction among patients receiving clopidogrel: A population-based study Journal Article 22 Oct 2012 Cardiovascular Health Drug-Drug Interactions
20 ICES Report: New findings highlight potential risks of common drug combination in cardiac patients Journal Article 01 May 2009 Cardiovascular Health Drug-Drug Interactions
21 The risk of hypotension following co-prescription of macrolide antibiotics and calcium-channel blockers Journal Article 22 Feb 2011 Cardiovascular Health Drug-Drug Interactions
22 Trimethoprim-sulfamethoxazole induced hyperkalaemia in elderly patients receiving spironolactone: Nested case-control study Journal Article 12 Sep 2011 Cardiovascular Health Drug-Drug Interactions
23 No increase in adverse events during aliskiren use among Ontario patients receiving angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers Journal Article 29 Mar 2013 Cardiovascular Health Drug-Drug Interactions
24 Hospitalization for hemorrhage among warfarin recipients prescribed amiodarone Journal Article 08 May 2013 Cardiovascular Health Drug-Drug Interactions
25 Ciprofloxacin-induced theophylline toxicity: A population-based study Journal Article 14 Jan 2011 Cardiovascular Health Drug-Drug Interactions
Please note that this report is NOT COMPLETE and is still in progress. Click below if you would like to continue.