Trends in opioid toxicities among people with and without opioid use disorder and the impact of the COVID-19 pandemic in Ontario, Canada

A population-based analysis

Across Canada, the COVID-19 pandemic occurred amidst an ongoing drug toxicity crisis, with elevated rates of substance-related harms observed nationally. Nearly two-thirds of all opioid-related deaths in Ontario occur among people with opioid use disorder (OUD), however it remains unknown if the pandemic state of emergency led to disproportionate increases in opioid toxicities among this population.

This study examined the trends in opioid toxicities overall and among people with and without OUD as well as the impact of the COVID-19 pandemic-related state of emergency on opioid toxicities.

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